Sotrovimab Vs Ivermectin: Key Features and Drug Comparison

Nowadays, people often try to compare the drugs – Sotrovimab and Ivermectin. And this is not surprising because both drugs are known for their practical effect on the sources of various infections. It is these drugs that science hopes for in the fight against Covid-19 and other diseases associated with the action of harmful viral and parasitic microorganisms.

In fact, the comparison of Sotrovimab vs Ivermectin is not entirely appropriate since both drugs are completely different classes of drugs. Not only do their structure and method of reception differ, but also the principle of influencing the source of the disease.

The key difference between Ivermectin and Sotrovimab

Ivermectin is a semi-synthetic substance in the form of tablets for oral administration. It is metabolised in the liver and affects harmful microorganisms by paralysing their nerve endings. Ivermectin is used to fight against parasites and viruses that can be localised in any organ or system of the body (gastrointestinal tract, skin, eyes, lungs and bronchial tubes, etc.).

In turn, Sotrovimab is a monoclonal antibody substance used to treat severe acute respiratory syndrome caused by respiratory infections. It is most commonly used in patients at high risk for progressing to severe, including hospitalisation or death. Unlike Ivermectin, Sotrovimab does not destroy pathogenic viruses but affects the body’s cells, providing them with increased protection. Sotrovimab restores the body’s immune defence and stimulates the regeneration of cells responsible for resisting viruses. This drug is used in the acute phase of respiratory diseases in combination with other medications. Thus, the treatment regimen is as follows: – Sotrovimab increases immunity and other drugs destroy the virus.

Also, there is a big difference between Sotrovimab and Ivermectin administration. As we mentioned previously, Ivermectin is designed for oral take-in. In turn, Sotrovimab is an injectable intravenous substance. As usual, patients get a single 500mg dose of diluted Sotrovimab substance, while Ivermectin is administered an hour before a meal every day.


Ivermectin and Sotrovimab are effective medicines whose main goal may seem the same – to help people get rid of acute diseases caused by infections. In turn, these medications are entirely different and should be taken in quite different situations. Ivermectin directly affects the activity of parasites and infections, while Sotrovimad stimulates the immune system to be more robust by building stable cells.