Ivermectin Drug Interactions in Humans: What Should You Know?

Сan You Take Ivermectin with Antibiotics?

Ivermectin is widely used in the antiparasitic protocol to treat some diseases. Its active ingredient paralyses parasites, leading to their death. Taking the drug may cause the following side effects:

  • dizziness;
  • faintness;
  • nausea;
  • rash;
  • blepharoedema, etc.

Besides, you should consider Ivermectin drug interactions to minimise the possible negative impact on your body.

Ivermectin should be taken with caution during treatment with sedative and anti-epileptic drugs. Besides, alcohol must be avoided, as well as a patient should be careful in the presence of diseases such as meningitis, African human trypanosomiasis, and HIV.

FLCCC about Ivermectin: Drug Interactions with COVID-19

Front Line COVID -19 Critical Care Alliance (FLCCC) was founded after the outbreak of the new Coronavirus COVID-19. Its members propose treating COVID-19 with drugs that were not previously considered antivirals.

Including FLCCC Ivermectin in the treatment protocol is based on the data on the efficacy of the drug in fighting the virus. However, other specialists think that using this medication to combat the virus requires a much too high dosage which is toxic for a human’s body.

Сan You Take Ivermectin with Antibiotics?

The drug doesn’t belong to antibiotics. It has antiparasitic but not antimicrobial effects. Considering this fact, taking Ivermectin together with antibiotics should have negative consequences. However, please inform your doctor about all the medications you take before starting Ivermectin treatment.

Is Ivermectin an Antiviral Drug: Research Data

Ivermectin’s anti-viral properties have been widely studied due to the spread of COVID-19. A number of studies have been done to determine whether the drug can be used in the treatment of a new disease. One of the studies showed that the medication proved effective for combating the virus in patients with mild to moderate COVID-19.

Can You Take Ivermectin with Ibuprofen?

No Ivermectin and Ibuprofen interactions were noticed. Because drugs belong to different categories, they have other effects and affect different body systems. At the same time, individual reactions are possible, which should be immediately reported to your doctor.

Ivermectin and Paracetamol: Interaction have not been identified

Paracetamol is classified as an anti-inflammatory and antipyretic drug. Its mechanism of action differs from the one of Ivermectin, which is why these drugs should not interact with each other.

However, there is no data regarding the interaction; it doesn’t exclude their occurrence in the future. In any case, closely monitor your condition when taking these drugs together and report any side effects to your doctor.


Ivermectin has been used in medical practice for a long time, and its interactions with other medications are well-studied. Experts don’t recommend using the drug with sedative and anti-epileptic agents. In other cases, negative drug interactions have not yet been identified.

Please remember: your individual reaction to the drug may differ from the common data. Consult your doctor before taking Ivermectin and report other medications your use.