Ivermectin and Intestines: the Effect of Drugs on the Gastrointestinal Tract

Does Ivermectin kill gut flora

Ivermectin is a broad-spectrum antiparasitic drug. This oral drug treats parasitic infections by destroying parasites in the intestines.

The action of Ivermectin in the intestines has been well studied during experimental and clinical studies. It was found that it affects the digestive system. How significant is this influence?

Ivermectin intestinal lining

If we talk about possible side effects, no data confirm that this drug has any effect on the intestinal lining. Ivermectin may cause mostly mild gastrointestinal adverse reactions, such as:

  • Stomach discomfort.
  • Decreased appetite.
  • Nausea.
  • Diarrhea.

Does Ivermectin kill gut flora?

This drug has proven antimicrobial properties. Its mechanism of action differs from that of antibacterial drugs but has some similarities. So, many people and health professionals want to know the answer to the question, “Does Ivermectin kill gut bacteria?”

Since Ivermectin has antibacterial properties, long use of the pills can affect the intestinal microflora and cause dysbacteriosis. Some reports support this assumption, but there are few studies on this problem. In any case, you will find no mention of such a side effect in the drug’s instructions.

Ivermectin: poop stopping

You can have such an unpleasant problem as constipation when taking Ivermectin tablets. Don’t take it lightly. Take measures to fight constipation effectively.

Here are typical recommendations for constipation:

  • Drink much water (at least 1.5–2 liters a day).
  • Eat fruits and vegetables rich in fiber.
  • Increase motor activity.
  • Take laxatives.

If you can’t deal with this condition on your own, seek medical help. Do it as soon as possible if you find blood in your stool or experience severe pain.

Ivermectin and “poop worms”

There are many strange stories about the use of Ivermectin. On the Internet, you can find reports of people claiming to have seen large parasites in their stool. Probably, it was intestinal mucus, which may look like worms to the untrained eye.

We should clarify that any parasites eventually go away from the intestines with the stool. However, because of their size, no one usually sees them.


When properly used and prescribed, Ivermectin tablets don’t significantly affect the digestive tract (esophagus, stomach, small and large intestines). If you have any side effects including those of the digestive system, consult your doctor. He will tell you how to eliminate or relieve them.